Nitrofurantoin-induced pulmonary reaction involving respiratory symptoms: case report.

Nitrofurantoin is an antimicrobial agent that is commonly used to treat urinary tract infections. It may also be used prophylactically for patients with recurrent urinary tract infection. Several cases and various clinical manifestations of pulmonary reactions to nitrofurantoin have been described in the literature. Early recognition of such reactions may prevent disability and death. This article describes a patient with an acute pulmonary reaction, specifically bronchiolitis obliterans organizing pneumonia (BOOP), which occurred after exposure to nitrofurantoin. The patient required intubation, and the condition was responsive to withdrawal of the drug followed by steroid therapy.